Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.63 |
| ▸ | PPARG | P37231 | 4/20 | 0.63 |
| ▸ | FABP2 | P12104 | 2/20 | 0.63 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PPARD | Q03181 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 10/20 | 0.52 |
| ▸ | CNR2 | P34972 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304554 | 0.89 | PPARA (0.54) | PPARAPPARGFABP2SLC22A12MEN1 | |
| SCHEMBL3687773 | 0.81 | PTGER4 (0.56) | PPARAPPARGFABP2SLC22A12MEN1 | |
| SCHEMBL10338889 | 0.81 | UTS2R (0.64) | MEN1CYP1A2MAPTCYP2C19KMT2A | |
| Clofibric Acid SCHEMBL102826 | 0.79 | PPARA (1.00) | PPARAPPARGFABP2SLC22A12MEN1 | |
| SCHEMBL12166209 | 0.79 | PPARA (0.69) | PPARAPPARGFABP2SLC22A12MEN1 | |
| Clofibric Acid SCHEMBL2227936 | 0.79 | PPARA (1.00) | PPARAPPARGFABP2SLC22A12MEN1 | |
| SCHEMBL11237830 | 0.78 | HPGD (0.44) | PPARAPPARGFABP2SMN1; SMN2ALDH1A1 | |
| Fenirofibrate SCHEMBL29024472 | 0.78 | PPARA (0.78) | PPARAPPARGFABP2SLC22A12MEN1 | |
| Fenirofibrate SCHEMBL2733696 | 0.78 | PPARA (0.78) | PPARAPPARGFABP2SLC22A12MEN1 | |
| SCHEMBL11569816 | 0.78 | PPARA (0.68) | PPARAPPARGFABP2SLC22A12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4370495-A | Process for the preparation of α-[4-(4-chlorobenzoylaminoethyl)-phenoxy]-isobutyric acid | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-25 | — | — | US | claimed |
| JP-2005298392-A | MEDICINAL COMPOSITION FOR PROPHYLAXIS OR TREATMENT OF REJECTION AFTER LIVER TRANSPLANTATION | KISSEI PHARMACEUT CO LTD | 2005-10-27 | — | — | JP | disclosed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |
| JP-2004149489-A | AGENT FOR PREVENTING AND TREATING INTRAHEPATIC STONE, OR AGENT FOR PREVENTING RELAPSE THEREOF | KISSEI PHARMACEUT CO LTD | 2004-05-27 | — | — | JP | disclosed |
| JP-2002249429-A | THERAPEUTIC AGENT FOR CHRONIC HEPTITIS C | KISSEI PHARMACEUT CO LTD | 2002-09-06 | — | — | JP | disclosed |
| WO-2002067920-A1 | REMEDIES FOR CHRONIC HEPATITIS C | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2002-09-06 | — | — | WO | disclosed |
| US-4370495-A | Process for the preparation of α-[4-(4-chlorobenzoylaminoethyl)-phenoxy]-isobutyric acid | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
| US-4370495-A | Process for the preparation of α-[4-(4-chlorobenzoylaminoethyl)-phenoxy]-isobutyric acid | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
| US-4370495-A | Process for the preparation of α-[4-(4-chlorobenzoylaminoethyl)-phenoxy]-isobutyric acid | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |