Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 4/20 | 0.59 |
| ▸ | FABP2 | P12104 | 2/20 | 0.59 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.59 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 7/20 | 0.49 |
| ▸ | CNR2 | P34972 | 5/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569483 | 0.84 | PPARA (0.71) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL102826 | 0.82 | PPARA (1.00) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL2227936 | 0.82 | PPARA (1.00) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Fenirofibrate SCHEMBL29024472 | 0.81 | PPARA (0.78) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Fenirofibrate SCHEMBL2733696 | 0.81 | PPARA (0.78) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL11798397 | 0.81 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL10634899 | 0.81 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL11798234 | 0.81 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL28571877 | 0.81 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 | |
| Clofibric Acid SCHEMBL317991 | 0.81 | PPARA (0.96) | PPARACYP1A2CYP3A4MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151303-A | Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions | BOEHRINGER MANNHEIM GMBH (DE) | 1979-04-24 | — | — | US | disclosed |