SCHEMBL6428868

SCHEMBL6428868

Oc1ccc(OC2CCC2Oc2ccc(O)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ESR2 Q92731 2/20 0.48
ESR1 P03372 1/20 0.48
LTA4H P09960 5/20 0.41
NR1H2 P55055 1/20 0.41
BAX Q07812 1/20 0.41
LMNA P02545 2/20 0.40
HIF1A Q16665 2/20 0.40
TYR P14679 2/20 0.40
APP P05067 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
CA12 O43570 1/20 0.40
GMNN O75496 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CYP3A4 P08684 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16902837 0.91 NPY1R (0.49) MEN1KMT2AESR2ESR1LTA4H
SCHEMBL10427435 0.80 TYR (0.37) MEN1KMT2AESR2ESR1LTA4H
SCHEMBL20455794 0.80 MEN1 (0.48) MEN1KMT2AESR2ESR1LTA4H
SCHEMBL16902836 0.80 MEN1 (0.48) MEN1KMT2AESR2ESR1LTA4H
SCHEMBL23542102 0.79 ESR2 (0.42) MEN1KMT2AESR2ESR1LTA4H
SCHEMBL1837838 0.76 PARP10 (0.53) MEN1KMT2AESR2ESR1LMNA
SCHEMBL10858201 0.76 PARP10 (0.58) MEN1KMT2AESR2ESR1ALDH1A1
SCHEMBL5651187 0.75 LSS (0.61)
SCHEMBL1402272 0.75 PARP10 (0.52) MEN1KMT2AESR2ESR1ALDH1A1
SCHEMBL1836444 0.75 PARP10 (0.52) MEN1KMT2AESR2ESR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505930-B2 Low gloss thermoplastic compositions, method of manufacture thereof and articles comprising the same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-29 US disclosed
US-20160009915-A1 LOW GLOSS THERMOPLASTIC COMPOSITIONS, METHOD OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-01-14 US disclosed
US-20130317141-A1 FLAME RETARDANT POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2013-11-28 US disclosed
US-6939651-B2 Electrophotographic photoconductor, and process cartridge and electrophotographic apparatus using the same RICOH COMPANY, LTD. (JP) 2005-09-06 US disclosed
US-20030059695-A1 Electrophotographic photoconductor, and process cartridge and electrophotographic apparatus using the same RICOH COMPANY, LTD. (JP) 2003-03-27 US disclosed