Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952169 | 0.89 | MEN1 (0.65) | GAAMAPTKDM4EALDH1A1SLC6A2 | |
| SCHEMBL5889215 | 0.89 | ALDH1A1 (0.58) | GAAMAPTKDM4EALDH1A1SLC6A2 | |
| SCHEMBL6429862 | 0.86 | GAA (0.60) | GAAMAPTSLC6A2SLC6A4HTT | |
| SCHEMBL15801112 | 0.86 | MAPT (0.61) | GAAMAPTKDM4EALDH1A1SLC6A2 | |
| SCHEMBL9051892 | 0.84 | KDM4E (0.51) | MAPTKDM4EALDH1A1 | |
| Acetamide SCHEMBL27608708 | 0.83 | SLC6A2 (0.65) | GAAMAPTKDM4EALDH1A1SLC6A2 | |
| SCHEMBL5888881 | 0.83 | ALDH1A1 (0.65) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6153849 | 0.82 | GAA (1.00) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL7241082 | 0.82 | SLC6A2 (0.71) | MAPTALDH1A1SLC6A2SLC6A4HTT | |
| SCHEMBL9050709 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974766-B | N-benzyl-3-phenylamide derivative, pharmaceutical composition containing same and application thereof | 中国药科大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-115974766-A | N-benzyl-3-phenylamide derivatives, pharmaceutical compositions containing same and uses thereof | 中国药科大学 | 2023-04-18 | — | — | CN | disclosed |
| US-20050222408-A1 | Heterocyclic amides with anti-tuberculosis activity | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2005-10-06 | — | — | US | disclosed |
| WO-2005007625-A2 | HETEROCYCLIC AMIDES WITH ANTI-TUBERCULOSIS ACTIVITY | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2005-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222408-A1 | Heterocyclic amides with anti-tuberculosis activity | TST, KAT5, NDUFS5 | GAA 4048/4885MAPT 4111/4885KDM4E 2025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.