Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 3/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29409705 | 1.00 | MEN1 (0.57) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6431289 | 0.88 | MEN1 (0.61) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6368127 | 0.87 | OPRM1 (0.57) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL31037193 | 0.87 | OPRM1 (0.57) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6367791 | 0.86 | OPRM1 (0.56) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6432366 | 0.85 | OPRM1 (0.57) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6431416 | 0.84 | OPRM1 (0.54) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6431423 | 0.84 | OPRM1 (0.54) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6428974 | 0.82 | OPRM1 (0.54) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6429015 | 0.82 | OPRM1 (0.52) | MEN1KMT2AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001764-A4 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2005-08-24 | — | — | EP | disclosed |
| EP-1001764-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999064395-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1998053814-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1998-12-03 | — | — | WO | disclosed |