Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2298604 | 0.95 | OPRM1 (0.56) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL6368127 | 0.87 | OPRM1 (0.57) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL31037193 | 0.87 | OPRM1 (0.57) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL6367791 | 0.86 | OPRM1 (0.56) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL29409705 | 0.85 | MEN1 (0.57) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL6429012 | 0.85 | MEN1 (0.57) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL6428974 | 0.84 | OPRM1 (0.54) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL6431468 | 0.84 | OPRM1 (0.54) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL6431423 | 0.84 | OPRM1 (0.54) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL6431416 | 0.84 | OPRM1 (0.54) | OPRM1OPRD1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001764-A4 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2005-08-24 | — | — | EP | disclosed |
| EP-1001764-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999064395-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1998053814-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1998-12-03 | — | — | WO | disclosed |