SCHEMBL6429043

SCHEMBL6429043

O=[PH](OCc1cn(Cc2ccccc2)nn1)OCc1cn(Cc2ccccc2)nn1

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 12/20 0.65
HSP90AB1 P08238 2/20 0.59
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
PTGS2 P35354 1/20 0.50
HRH4 Q9H3N8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2190939 0.83 HSP90AB1 (0.82) CYP19A1HSP90AB1NPC1RAB9AHRH4
SCHEMBL1715655 0.80 CYP19A1 (0.70) CYP19A1HSP90AB1NPC1RAB9AHRH4
SCHEMBL84637 0.79 CYP19A1 (1.00) CYP19A1HSP90AB1PTGS2
SCHEMBL28676360 0.78 CYP19A1 (0.66) CYP19A1HSP90AB1NPC1RAB9AHRH4
SCHEMBL12673479 0.78 CYP19A1 (0.76) CYP19A1HSP90AB1NPC1RAB9APTGS2
SCHEMBL28329956 0.77 CYP19A1 (0.62) CYP19A1HSP90AB1NPC1RAB9A
SCHEMBL14680115 0.76 CYP19A1 (0.82) CYP19A1HSP90AB1RAB9APTGS2
SCHEMBL3103838 0.76 CYP19A1 (0.68) CYP19A1HSP90AB1NPC1RAB9AHRH4
SCHEMBL12022159 0.76 KCNMA1 (0.69) CYP19A1HSP90AB1NPC1RAB9AHRH4
SCHEMBL3766130 0.75 HSP90AB1 (0.66) CYP19A1HSP90AB1NPC1RAB9AHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1517972-A1 METAL POLISH COMPOSITION, POLISHING METHOD USING THE COMPOSITION AND METHOD FOR PRODUCING WAFER USING THE POLISHING METHOD Showa Denko K.K. (JP) 2005-03-30 EP disclosed
WO-2003104350-A1 METAL POLISH COMPOSITION, POLISHING METHOD USING THE COMPOSITION AND METHOD FOR PRODUCING WAFER USING THE POLISHING METHOD SHOWA DENKO K.K. (JP) 2003-12-18 WO disclosed