Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 1.00 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680115 | 0.90 | CYP19A1 (0.82) | CYP19A1HSP90AB1PTGS2MGAM | |
| SCHEMBL29054411 | 0.90 | CYP19A1 (0.82) | CYP19A1HSP90AB1PTGS2 | |
| SCHEMBL12673479 | 0.86 | CYP19A1 (0.76) | CYP19A1HSP90AB1PTGS2 | |
| SCHEMBL2190939 | 0.85 | HSP90AB1 (0.82) | CYP19A1HSP90AB1 | |
| SCHEMBL21349159 | 0.85 | CYP19A1 (0.74) | CYP19A1HSP90AB1 | |
| SCHEMBL14680109 | 0.85 | CYP19A1 (1.00) | CYP19A1PTGS2MGAM | |
| SCHEMBL1715655 | 0.83 | CYP19A1 (0.70) | CYP19A1HSP90AB1 | |
| SCHEMBL30757737 | 0.80 | CYP19A1 (0.67) | CYP19A1 | |
| SCHEMBL6429043 | 0.79 | CYP19A1 (0.65) | CYP19A1HSP90AB1PTGS2 | |
| SCHEMBL18579845 | 0.79 | CYP19A1 (0.65) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526876-A | A kind of preparation method of organic nitrine and Terminal Acetylenes synthesis 1,4- substitution 1,2,3- triazole | UNIV LESHAN NORMAL | 2019-12-03 | — | — | CN | disclosed |
| CN-106588788-B | The method of one pot of two-step method synthesis 1,2,3- triazole compound | 河南师范大学 | 2019-07-16 | — | — | CN | disclosed |
| EP-1507769-B2 | COPPER-CATALYSED LIGATION OF AZIDES AND ACETYLENES | SCRIPPS RESEARCH INST (US) | 2017-10-11 | — | — | EP | disclosed |
| US-20160214946-A1 | CATALYSED LIGATION OF AZIDES AND ACETYLENES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214946-A1 | CATALYSED LIGATION OF AZIDES AND ACETYLENES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-07-28 | — | — | US | disclosed |
| US-9302997-B2 | Copper-catalysed ligation of azides and acetylenes | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-05 | — | — | US | disclosed |
| US-9302997-B2 | Copper-catalysed ligation of azides and acetylenes | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-05 | — | — | US | disclosed |
| US-20150232432-A1 | COPPER-CATALYSED LIGATION OF AZIDES AND ACETYLENES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-08-20 | — | — | US | disclosed |
| US-20150232432-A1 | COPPER-CATALYSED LIGATION OF AZIDES AND ACETYLENES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-08-20 | — | — | US | disclosed |
| US-9040716-B2 | Copper-catalysed ligation of azides and acetylenes | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-05-26 | — | — | US | disclosed |
| US-20110105764-A1 | Copper-catalysed ligation of azides and acetylenes | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-05-05 | — | — | US | disclosed |
| US-20110105764-A1 | Copper-catalysed ligation of azides and acetylenes | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-05-05 | — | — | US | disclosed |
| EP-2226316-A1 | Copper-catalysed ligation of azides and acetylenes | The Scripps Research Institute (US) | 2010-09-08 | — | — | EP | disclosed |
| US-7763736-B2 | Contacting an organic azide and a terminal alkyne with a source of reactive Cu(I) ion for a time sufficient to form by cycloaddition a 1,4-disubstituted 1,2,3-triazole; high yields and high purity | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-07-27 | — | — | US | disclosed |
| US-7763736-B2 | Contacting an organic azide and a terminal alkyne with a source of reactive Cu(I) ion for a time sufficient to form by cycloaddition a 1,4-disubstituted 1,2,3-triazole; high yields and high purity | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-07-27 | — | — | US | disclosed |
| EP-1507769-B1 | COPPER-CATALYSED LIGATION OF AZIDES AND ACETYLENES | SCRIPPS RESEARCH INST (US) | 2010-05-26 | — | — | EP | disclosed |
| US-20080214831-A1 | Contacting an organic azide and a terminal alkyne with a source of reactive Cu(I) ion for a time sufficient to form by cycloaddition a 1,4-disubstituted 1,2,3-triazole; high yields and high purity | THE SCRIPPS RESEARCH INSTITUTE | 2008-09-04 | — | — | US | disclosed |
| US-20080214831-A1 | Contacting an organic azide and a terminal alkyne with a source of reactive Cu(I) ion for a time sufficient to form by cycloaddition a 1,4-disubstituted 1,2,3-triazole; high yields and high purity | THE SCRIPPS RESEARCH INSTITUTE | 2008-09-04 | — | — | US | disclosed |
| US-7375234-B2 | regiospecifically ligates azides and terminal acetylenes to give only 1,4-disubstituted [1,2,3]-triazoles; stepwise Huisgen cycloaddition process catalyzed by copper | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375234-B2 | regiospecifically ligates azides and terminal acetylenes to give only 1,4-disubstituted [1,2,3]-triazoles; stepwise Huisgen cycloaddition process catalyzed by copper | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232432-A1 | COPPER-CATALYSED LIGATION OF AZIDES AND ACETYLENES | SOD1, AOC3, AOC2 | CYP19A1 1934/4885HSP90AB1 4428/4885PTGS2 2311/4885 |
| US-20080214831-A1 | Contacting an organic azide and a terminal alkyne with a source of reactive Cu(I) ion for a time sufficient to form by cycloaddition a 1,4-disubstituted 1,2,3-triazole; high yields and high purity | AOC3, AOC2, ADH1C | CYP19A1 3766/4885HSP90AB1 3258/4885PTGS2 3139/4885 |
| US-20160214946-A1 | CATALYSED LIGATION OF AZIDES AND ACETYLENES | AOC3, AOC2, KARS1 | CYP19A1 1159/4885HSP90AB1 4081/4885PTGS2 2767/4885 |
| US-20110105764-A1 | Copper-catalysed ligation of azides and acetylenes | AOC3, ADH1C, AOC2 | CYP19A1 2969/4885HSP90AB1 2943/4885PTGS2 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.