Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 20/20 | 0.67 |
| ▸ | MMP2 | P08253 | 5/20 | 0.67 |
| ▸ | MMP3 | P08254 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6428620 | 0.96 | BMP1 (0.62) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6430136 | 0.93 | BMP1 (0.64) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL27586685 | 0.93 | BMP1 (0.64) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL27567239 | 0.90 | BMP1 (0.80) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL27567206 | 0.90 | BMP1 (0.80) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6428411 | 0.90 | BMP1 (0.80) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6428682 | 0.90 | BMP1 (0.80) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6428347 | 0.90 | BMP1 (0.83) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL6429991 | 0.89 | BMP1 (0.69) | BMP1MMP2MMP3PDE4APDE4B | |
| SCHEMBL27567303 | 0.89 | BMP1 (0.62) | BMP1MMP2MMP3PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897306-B2 | 3-heterocyclylpropanohydroxamic acids | PFIZER PRODUCTS, INC. (US) | 2005-05-24 | — | — | US | claimed |
| US-6897306-B2 | 3-heterocyclylpropanohydroxamic acids | PFIZER PRODUCTS, INC. (US) | 2005-05-24 | — | — | US | disclosed |
| EP-1240152-B1 | OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LTD (GB) | 2004-12-08 | — | — | EP | disclosed |
| US-20030119807-A1 | 3-Heterocyclylpropanohydroxamic acids | BAILEY SIMON (US) | 2003-06-26 | — | — | US | disclosed |
| EP-1240152-A1 | OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS | Pfizer Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001047901-A1 | OX(ADI)AZOLYL-HYDROXAMIC ACIDS USEFUL AS PROCOLLAGEN C-PROTEINASE INHIBITORS | PFIZER LIMITED (GB) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119807-A1 | 3-Heterocyclylpropanohydroxamic acids | CPA1, MMP1, PREP | BMP1 79/4885MMP2 11/4885MMP3 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.