SCHEMBL6429481

SCHEMBL6429481

CCCC(CC1(C(=O)NC2(CO)CCCC2)CCCC1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MME P08473 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5924911 0.85 MME (1.00) MME
SCHEMBL5924871 0.85 MME (1.00) MME
SCHEMBL5924879 0.85 MME (1.00) MME
SCHEMBL7450171 0.80 MME (0.67) MME
SCHEMBL7449713 0.76 MME (0.61) MME
SCHEMBL7442734 0.74 MME (0.73) MME
SCHEMBL7442730 0.74 MME (0.73) MME
SCHEMBL5924940 0.73 MME (1.00) MME
SCHEMBL5924934 0.73 MME (1.00) MME
SCHEMBL5924965 0.73 MME (1.00) MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050070499-A1 Compounds for the treatment of female sexual dysfunction PFIZER INC. 2005-03-31 US disclosed
EP-1097719-B1 NEP inhibitors for the treatment of female sexual dysfunction PFIZER LTD (GB) 2004-12-22 EP disclosed
US-20040254153-A1 Compounds for the treatment of female sexual dysfunction PFIZER INC 2004-12-16 US disclosed
EP-1481667-A1 NEP inhibitors for the treatment of female sexual dysfunction Pfizer Limited (GB) 2004-12-01 EP disclosed
US-6734186-B1 PHOSPHODIESTERASE 2 INHIBITOR PFIZER INC. 2004-05-11 US disclosed
CN-1438991-A Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase PFIZER CIMITED (US) 2003-08-27 CN disclosed
US-20020052370-A1 Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase PFIZER, INC. 2002-05-02 US disclosed
EP-1097707-A1 Treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097719-A1 NEP inhibitors for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097706-A1 Phosphodiesterase inhibitors for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed
EP-1097718-A1 NPY antagonists for the treatment of female sexual dysfunction Pfizer Limited (GB) 2001-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040254153-A1 Compounds for the treatment of female sexual dysfunction FSHR, SHBG, PDE3A MME 2886/4885
US-20020052370-A1 Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase ENGASE, ENPEP, CPN1 MME 7/4885
US-20050070499-A1 Compounds for the treatment of female sexual dysfunction FSHR, SHBG, PDE3A MME 2886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.