Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.76 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20961446 | 0.92 | HDAC6 (0.76) | HDAC6HDAC1HDAC10HDAC3HDAC2 | |
| SCHEMBL12951842 | 0.86 | HDAC6 (1.00) | HDAC6HDAC1HDAC10HDAC3HDAC2 | |
| SCHEMBL6341009 | 0.82 | HDAC6 (0.71) | HDAC6HDAC1HDAC10HDAC8CA1 | |
| SCHEMBL6342434 | 0.82 | HDAC1 (0.70) | HDAC6HDAC1CA1CA2 | |
| SCHEMBL6422248 | 0.81 | HDAC1 (0.69) | HDAC6HDAC1CA1CA2 | |
| SCHEMBL12951838 | 0.81 | HDAC6 (0.72) | HDAC6HDAC1HDAC10HDAC3HDAC2 | |
| SCHEMBL1003485 | 0.81 | HDAC6 (0.77) | HDAC6HDAC1HDAC10HDAC3HDAC2 | |
| Hydrochloric Acid SCHEMBL6339587 | 0.81 | HDAC1 (0.69) | HDAC6HDAC1CA1CA2 | |
| Hydrochloric Acid SCHEMBL9615118 | 0.80 | HDAC1 (0.67) | HDAC6HDAC1CA1CA2 | |
| SCHEMBL6420858 | 0.80 | HDAC1 (0.58) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6964970-B2 | Antibacterial compounds | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2005-11-15 | — | — | US | disclosed |
| EP-1180030-B1 | ANTIBACTERIAL COMPOUNDS | AFFINIUM PHARM INC (CA) | 2004-11-24 | — | — | EP | disclosed |
| US-20030232850-A1 | Antibacterial compounds | DEBIOPHARM INTERNATIONAL SA (CH) | 2003-12-18 | — | — | US | disclosed |
| US-6573272-B1 | Antibacterial compounds | AFFINIUM PHARMACEUTICALS, INC. (CA) | 2003-06-03 | — | — | US | disclosed |
| EP-1180030-A4 | ANTIBACTERIAL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1180030-A1 | ANTIBACTERIAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2002-02-20 | — | — | EP | disclosed |
| WO-2000072846-A1 | ANTIBACTERIAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232850-A1 | Antibacterial compounds | RER1, FAR1, REL | HDAC6 317/4885HDAC1 61/4885HDAC10 421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.