Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078791 | 0.90 | MEN1 (0.61) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL6079658 | 0.88 | GAA (0.62) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL6078632 | 0.84 | GAA (0.60) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL7663909 | 0.84 | PLAU (0.66) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL7663907 | 0.82 | MEN1 (0.58) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL7782154 | 0.82 | ALDH1A1 (0.77) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL7348029 | 0.82 | MEN1 (0.70) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL12010883 | 0.81 | BDKRB1 (0.67) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL16127963 | 0.80 | ALDH1A1 (0.69) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL6079716 | 0.80 | MEN1 (0.53) | MEN1KMT2APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1181271-B1 | NAPHTHALENE UREAS AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2005-01-19 | — | — | EP | disclosed |