Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239484 | 0.84 | DGKA (0.48) | DGKACYP3A4P2RY10GPR34NAAA | |
| SCHEMBL28392407 | 0.84 | DGKA (0.52) | DGKAP2RY10GPR34NAAAHTR2C | |
| SCHEMBL2397915 | 0.82 | DGKA (0.50) | DGKAP2RY10GPR34NAAAHTR2C | |
| SCHEMBL11573694 | 0.82 | CYP3A4 (0.47) | CYP3A4ALDH1A1ATMLPAR3LPAR1 | |
| SCHEMBL9290975 | 0.81 | DGKA (0.46) | DGKACYP3A4P2RY10GPR34NAAA | |
| SCHEMBL340419 | 0.81 | DGKA (0.46) | DGKACYP3A4P2RY10GPR34NAAA | |
| SCHEMBL29025932 | 0.80 | DGKA (0.44) | DGKACYP3A4P2RY10GPR34NAAA | |
| SCHEMBL15951826 | 0.79 | DGKA (0.47) | DGKACYP3A4P2RY10GPR34NAAA | |
| SCHEMBL2237629 | 0.79 | DGKA (0.52) | DGKACYP3A4P2RY10GPR34NAAA | |
| SCHEMBL15951765 | 0.79 | DGKA (0.47) | DGKACYP3A4P2RY10GPR34NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4279594-A | — | — | None | — | — | JP | disclosed |
| EP-1308451-B1 | Process for the preparation of carboxyethylmethyl phosphinic acid glycol ester | CLARIANT GMBH (DE) | 2005-01-19 | — | — | EP | disclosed |
| EP-1308451-A1 | Process for the preparation of carboxyethylmethyl phosphinic acid glycol ester | Clariant GmbH (DE) | 2003-05-07 | — | — | EP | disclosed |
| EP-0436937-B1 | Process for synthesis of methyl-(2-carboalkoxy-ethyl)-phosphinic acid alkyl esters | HOECHST SCHERING AGREVO GMBH (DE) | 1995-04-05 | — | — | EP | disclosed |
| JP-H04279594-A | SYNTHESIS METHDO OF ALKYL METHYL-(2-CARBOALKOXYETHYL) PHOSPHINATE | HOECHST AG | 1992-10-05 | — | — | JP | disclosed |
| EP-0436937-A1 | Process for synthesis of methyl-(2-carboalkoxy-ethyl)-phosphinic acid alkyl esters | Hoechst Schering AgrEvo GmbH (DE) | 1991-07-17 | — | — | EP | disclosed |