Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2397289 | 0.89 | DGKA (0.44) | DGKANAAAALDH1A1HTR2CDNM1 | |
| SCHEMBL28392407 | 0.87 | DGKA (0.52) | DGKANAAAALDH1A1HTR2CATM | |
| Butane SCHEMBL2242245 | 0.85 | DGKA (0.50) | DGKANAAAALDH1A1HTR2CATM | |
| SCHEMBL1037012 | 0.84 | DGKA (0.48) | DGKANAAAALDH1A1HTR2CATM | |
| SCHEMBL9290907 | 0.84 | DGKA (0.48) | DGKANAAAALDH1A1HTR2CATM | |
| Phosphoric Acid SCHEMBL27914728 | 0.82 | DGKA (0.61) | DGKANAAAALDH1A1HTR2CATM | |
| SCHEMBL6429626 | 0.82 | DGKA (0.47) | DGKANAAAALDH1A1HTR2CATM | |
| SCHEMBL8845338 | 0.81 | DGKA (0.50) | DGKANAAAALDH1A1HTR2CATM | |
| SCHEMBL28437253 | 0.81 | DGKA (0.55) | DGKANAAAALDH1A1HTR2CDNM1 | |
| SCHEMBL8845277 | 0.81 | DGKA (0.50) | DGKANAAAALDH1A1HTR2CATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104761583-A | METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID | MEIJI SEIKA KAISHA | 2015-07-08 | — | — | CN | disclosed |
| US-8017797-B2 | Method for producing phosphorus-containing α-keto acid | MEIJI SEIKA KAISHA LTD. (JP) | 2011-09-13 | — | — | US | disclosed |
| US-20100063313-A1 | METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID | MEIJI SEIKA KAISHA LTD., (JP) | 2010-03-11 | — | — | US | disclosed |
| CN-101641363-A | Method for producing phosphorus-containing alpha-keto acid | MEIJI SEIKA KAISHA JP | 2010-02-03 | — | — | CN | disclosed |
| EP-2133356-A1 | PROCESS FOR PRODUCTION OF PHOSPHORUS-CONTAINING -KETO ACID | Meiji Seika Kaisha, Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
| EP-0436937-B1 | Process for synthesis of methyl-(2-carboalkoxy-ethyl)-phosphinic acid alkyl esters | HOECHST SCHERING AGREVO GMBH (DE) | 1995-04-05 | — | — | EP | disclosed |
| US-5153346-A | PROCESS FOR THE SYNTHESIS OF ALKYL METHYL-(2-CARBOALKOXY-ETHYL)PHOSPHINATES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-06 | — | — | US | disclosed |
| EP-0436937-A1 | Process for synthesis of methyl-(2-carboalkoxy-ethyl)-phosphinic acid alkyl esters | Hoechst Schering AgrEvo GmbH (DE) | 1991-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063313-A1 | METHOD FOR PRODUCING PHOSPHORUS-CONTAINING ALPHA-KETO ACID | PRKAB1, PRKAB2, PLCB1 | DGKA 494/4885NAAA 241/4885ALDH1A1 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.