Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2259800 | 0.92 | HTT (0.51) | HTTKMT2AMEN1NPSR1LMNA | |
| SCHEMBL20268246 | 0.92 | HTT (0.51) | HTTKMT2AMEN1NPSR1LMNA | |
| SCHEMBL2464249 | 0.91 | HTT (0.50) | HTTKMT2AMEN1NPSR1LMNA | |
| Hydrochloric Acid SCHEMBL11830306 | 0.89 | HTT (0.49) | HTTKMT2AMEN1NPSR1LMNA | |
| SCHEMBL12498396 | 0.83 | HTT (0.63) | HTTKMT2AMEN1NPSR1CHRM3 | |
| SCHEMBL6420648 | 0.81 | HTT (0.43) | HTTKMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL6424261 | 0.81 | HTT (0.40) | HTTKMT2AMEN1TSHRNPC1 | |
| SCHEMBL834473 | 0.78 | HTT (0.61) | HTTKMT2AMEN1NPSR1LMNA | |
| SCHEMBL3978591 | 0.77 | NPC1 (0.49) | KMT2ASMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL1522068 | 0.76 | HTT (0.59) | HTTKMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007614-A1 | MONOAMINE OXIDASE INHIBITORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 6011 (US) | 2005-01-27 | — | — | WO | disclosed |