Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL11390624 | 1.00 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL27739523 | 0.97 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL5702864 | 0.92 | GPR84 (0.59) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL25247249 | 0.91 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL28859851 | 0.91 | SLC22A6 (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL7544486 | 0.91 | LMNA (0.65) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL1638937 | 0.88 | LMNA (0.61) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL28032942 | 0.88 | LMNA (0.61) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL27569630 | 0.88 | LMNA (0.69) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hexanoate SCHEMBL18825549 | 0.87 | AKR1B1 (0.76) | LMNATSHRSLC22A6GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132630-A2 | BIODEGRADABLE THERMOPLASTIC POLYETHER ESTER ELASTOMER | 이성율 | 2023-07-13 | — | — | WO | claimed |
| WO-2023132630-A2 | BIODEGRADABLE THERMOPLASTIC POLYETHER ESTER ELASTOMER | 이성율 | 2023-07-13 | — | — | WO | disclosed |
| WO-2017031409-A1 | PERFORATED POLYOLEFIN FILMS | ACHILLES USA, INC. (US) | 2017-02-23 | — | — | WO | disclosed |
| US-20050197413-A1 | Flexible molded parts of expanded polyurethane and their use | BAYER MATERIALSCIENCE AG (DE) | 2005-09-08 | — | — | US | disclosed |
| EP-0089780-B2 | A polyurethane elastomer and an improved hypoallergenic polyurethane flexible glove prepared therefrom | DESERET MEDICAL INC (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5073425-A | Polyvinyl chloride surface covering compositions having reduced electrical resistivities | ARMSTRONG WORLD INDUSTRIES, INC. (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0089780-B1 | A POLYURETHANE ELASTOMER AND AN IMPROVED HYPOALLERGENIC POLYURETHANE FLEXIBLE GLOVE PREPARED THEREFROM | Deseret Medical, Inc. (US) | 1988-05-25 | — | — | EP | disclosed |
| US-4647643-A | MEDICAL TUBING, POLYETHERSILOXANE COPOLYMER | BECTON, DICKINSON AND COMPANY (US) | 1987-03-03 | — | — | US | disclosed |
| US-4463156-A | Polyurethane elastomer and an improved hypoallergenic polyurethane flexible glove prepared therefrom | WARNER-LAMBERT CO., INC. (US) | 1984-07-31 | — | — | US | disclosed |
| EP-0089780-A2 | A polyurethane elastomer and an improved hypoallergenic polyurethane flexible glove prepared therefrom | Deseret Medical, Inc. (US) | 1983-09-28 | — | — | EP | disclosed |