Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.52 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3529969 | 0.95 | CHRNB2 (0.50) | CHRNB2CHRNA4ORAI1KMT2AGRM2 | |
| SCHEMBL7105377 | 0.74 | CHRNB2 (0.84) | CHRNB2CHRNA4 | |
| SCHEMBL8380050 | 0.71 | P4HTM (0.35) | CHRNB2CHRNA4KMT2ACYP3A4CYP2D6 | |
| SCHEMBL7101849 | 0.70 | CHRNB2 (0.81) | CHRNB2CHRNA4CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12667879 | 0.70 | CHRNB2 (0.62) | CHRNB2CHRNA4KMT2ACYP3A4CYP2D6 | |
| SCHEMBL12827198 | 0.70 | CHRNB2 (1.00) | CHRNB2CHRNA4 | |
| SCHEMBL22831347 | 0.70 | CHRNB2 (0.87) | CHRNB2CHRNA4 | |
| SCHEMBL15434709 | 0.70 | CHRNB2 (0.60) | CHRNB2CHRNA4ORAI1KMT2A | |
| SCHEMBL29784945 | 0.70 | CHRNB2 (1.00) | CHRNB2CHRNA4 | |
| SCHEMBL7107128 | 0.69 | KIF11 (0.51) | KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517903-A2 | MARKED MALEIMIDE COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR MARKING MACROMOLECULES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002984-A2 | MARKED MALEIMIDE COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR MARKING MACROMOLECULES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2004-01-08 | — | — | WO | disclosed |