SCHEMBL6429901

SCHEMBL6429901

Cc1cccc(C)c1/N=C1C(=N\c2c(C)cccc2C)/OCCN/1C

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
FGB P02675 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6429905 1.00 MEN1 (0.33) MEN1GAAMAPK1KMT2AFGB
SCHEMBL6430326 0.81 MEN1 (0.32) MEN1GAAMAPK1KMT2A
SCHEMBL6429903 0.81 MEN1 (0.32) MEN1GAAMAPK1KMT2A
SCHEMBL5590435 0.79 MEN1 (0.35) MEN1GAAKMT2A
SCHEMBL5590431 0.79 MEN1 (0.35) MEN1GAAKMT2A
SCHEMBL5587606 0.78 MEN1 (0.34) MEN1GAAKMT2A
SCHEMBL6430829 0.77 MEN1 (0.36) MEN1KMT2A
SCHEMBL6430827 0.77 MEN1 (0.36) MEN1KMT2A
SCHEMBL5589744 0.76 ALDH1A1 (0.34) MEN1GAAKMT2A
SCHEMBL5589745 0.76 ALDH1A1 (0.34) MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050090630-A1 Supported group 8-10 transition metal olefin polymerization catalysts EASTMAN CHEMICAL COMPANY (US) 2005-04-28 US disclosed
US-6822062-B2 FOR USE IN ADDITION POLYMERIZATION OF OLEFINS EASTMAN CHEMICAL COMPANY 2004-11-23 US disclosed
US-20040029720-A1 Supported group 8-10 transition metal olefin polymerization catalysts EASTMAN CHEMICAL COMPANY 2004-02-12 US disclosed
US-6660677-B1 Supported group 8-10 transition metal olefin polymerization catalysts EASTMAN CHEMICAL COMPANY 2003-12-09 US disclosed
US-20020058768-A1 Supported group 8-10 transition metal Olefin polymerization catalysts E. I. DU PONT DE NEMOURS AND COMPANY 2002-05-16 US disclosed
US-6303720-B1 E.G., NICKEL COMPLEX OF 2,3-BIS(2,6-DIMETHYLPHENYLIMINO)-(1,4)-DITHIANE EASTMAN CHEMICAL COMPANY 2001-10-16 US disclosed
EP-1082362-A1 SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2001-03-14 EP disclosed
US-6103658-A Olefin polymerization catalysts containing group 8-10 transition metals, processes employing such catalysts and polymers obtained therefrom EASTMAN CHEMICAL COMPANY (US) 2000-08-15 US disclosed
EP-0973762-A2 OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS , PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM EASTMAN CHEMICAL COMPANY (US) 2000-01-26 EP disclosed
WO-1999062968-A1 SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS EASTMAN CHEMICAL COMPANY (US) 1999-12-09 WO disclosed
WO-1998040374-A2 OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS, PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM EASTMAN CHEMICAL COMPANY (US) 1998-09-17 WO disclosed