Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430827 | 1.00 | MEN1 (0.36) | MEN1HSP90AA1KMT2AATMMAP3K14 | |
| SCHEMBL6429901 | 0.77 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL6429905 | 0.77 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL14276100 | 0.74 | ITGB2 (0.32) | SIGMAR1ITGB2ICAM1ITGALLMNA | |
| SCHEMBL6434164 | 0.74 | GABRA1 (0.39) | KMT2ACYP1A2CA1CA2ALDH1A1 | |
| SCHEMBL6434166 | 0.74 | GABRA1 (0.39) | KMT2ACYP1A2CA1CA2ALDH1A1 | |
| SCHEMBL10831788 | 0.70 | POLB (0.39) | MEN1HSP90AA1KMT2AATMPOLB | |
| SCHEMBL5590260 | 0.70 | POLB (0.39) | MEN1HSP90AA1KMT2AATMPOLB | |
| SCHEMBL5590258 | 0.70 | POLB (0.39) | MEN1HSP90AA1KMT2AATMPOLB | |
| SCHEMBL5587514 | 0.69 | BRD4 (0.38) | MEN1HSP90AA1KMT2AATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090630-A1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY (US) | 2005-04-28 | — | — | US | disclosed |
| US-6822062-B2 | FOR USE IN ADDITION POLYMERIZATION OF OLEFINS | EASTMAN CHEMICAL COMPANY | 2004-11-23 | — | — | US | disclosed |
| US-20040029720-A1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY | 2004-02-12 | — | — | US | disclosed |
| US-6660677-B1 | Supported group 8-10 transition metal olefin polymerization catalysts | EASTMAN CHEMICAL COMPANY | 2003-12-09 | — | — | US | disclosed |
| US-20020058768-A1 | Supported group 8-10 transition metal Olefin polymerization catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-05-16 | — | — | US | disclosed |
| US-6303720-B1 | E.G., NICKEL COMPLEX OF 2,3-BIS(2,6-DIMETHYLPHENYLIMINO)-(1,4)-DITHIANE | EASTMAN CHEMICAL COMPANY | 2001-10-16 | — | — | US | disclosed |
| EP-1082362-A1 | SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2001-03-14 | — | — | EP | disclosed |
| US-6103658-A | Olefin polymerization catalysts containing group 8-10 transition metals, processes employing such catalysts and polymers obtained therefrom | EASTMAN CHEMICAL COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0973762-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS , PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999062968-A1 | SUPPORTED GROUP 8-10 TRANSITION METAL OLEFIN POLYMERIZATION CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |
| WO-1998040374-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS, PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 1998-09-17 | — | — | WO | disclosed |