Biphenyl

Biphenyl

SCHEMBL6429902

O=P(O)(O)Oc1ccc(-c2ccc(O)cc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.64
MMP3 P08254 1/20 0.56
BCL2L1 Q07817 1/20 0.56
LTA4H P09960 1/20 0.45
NR1H2 P55055 1/20 0.45
BAX Q07812 1/20 0.45
DEGS1 O15121 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
ESR1 P03372 5/20 0.44
ESR2 Q92731 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
INPPL1 O15357 2/20 0.43
INPP5A Q14642 2/20 0.43
BLM P54132 1/20 0.43
ACP3 P15309 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28533856 0.98 SRC (0.67) SRCMMP3BCL2L1LTA4HNR1H2
SCHEMBL2214337 0.92 SRC (0.75) SRCCA1CA2RAB9AINPPL1
Biphenyl SCHEMBL27733067 0.92 SRC (0.75) SRCCA1CA2RAB9AINPPL1
Water SCHEMBL27699573 0.90 SRC (0.72) SRCCA1CA2RAB9AINPPL1
SCHEMBL22064858 0.87 SRC (0.67) SRCCA1CA2INPPL1INPP5A
Phenyl Dihydrogen Phosphate SCHEMBL28144635 0.86 SRC (0.79) SRCLTA4HNR1H2BAXCA1
Biphenyl SCHEMBL12978995 0.86 SRC (0.86) SRCCA1CA2INPPL1INPP5A
Biphenyl SCHEMBL6118426 0.86 SRC (0.86) SRCCA1CA2INPPL1INPP5A
SCHEMBL131227 0.86 SRC (0.62) SRCLTA4HNR1H2BAXCA1
SCHEMBL6118470 0.85 MMP3 (0.56) SRCMMP3BCL2L1LTA4HNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1327635-B1 Preparation of phenylphosphate esters of 4,4'-biphenol BROMINE COMPOUNDS LTD (IL) 2005-08-31 EP disclosed
US-20030171463-A1 Preparation of phenylphosphate esters of 4,4'-biphenol BROMINE COMPOUNDS LTD. (IL) 2003-09-11 US disclosed
EP-1327635-A1 Preparation of phenylphosphate esters of 4,4'-biphenol Bromine Compounds Ltd. (IL) 2003-07-16 EP disclosed