SCHEMBL6429941

SCHEMBL6429941

CC(C)c1cccc(C(C)C)c1NC(=O)C(=O)Nc1c(C(C)C)cccc1C(C)C

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.65
LMNA P02545 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
MEN1 O00255 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
NLRP3 Q96P20 2/20 0.53
LPAR1 Q92633 1/20 0.53
SOAT2 O75908 1/20 0.51
SOAT1 P35610 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30977623 0.90 KMT2A (0.64) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL30977624 0.90 KMT2A (0.64) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL462304 0.87 LPAR1 (0.66) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL18415612 0.87 KMT2A (0.56) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL2947587 0.87 KMT2A (0.56) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL1726368 0.85 KMT2A (0.62) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL8845511 0.85 KMT2A (0.68) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL3147905 0.85 KMT2A (0.54) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL9843936 0.83 SMN1; SMN2 (0.77) KMT2ALMNASMN1; SMN2MEN1TDP1
SCHEMBL8819876 0.83 KMT2A (0.61) KMT2ALMNASMN1; SMN2MEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9051399-B2 Method for producing polar group-containing olefin copolymers SHOWA DENKO K.K. (JP) 2015-06-09 US disclosed
US-9051399-B2 Method for producing polar group-containing olefin copolymers SHOWA DENKO K.K. (JP) 2015-06-09 US disclosed
US-20130165607-A1 METHOD FOR PRODUCING POLAR GROUP-CONTAINING OLEFIN COPOLYMERS SHOWA DENKO K.K. (JP) 2013-06-27 US disclosed
US-20130165607-A1 METHOD FOR PRODUCING POLAR GROUP-CONTAINING OLEFIN COPOLYMERS SHOWA DENKO K.K. (JP) 2013-06-27 US disclosed
US-20050090630-A1 Supported group 8-10 transition metal olefin polymerization catalysts EASTMAN CHEMICAL COMPANY (US) 2005-04-28 US disclosed
US-6822062-B2 FOR USE IN ADDITION POLYMERIZATION OF OLEFINS EASTMAN CHEMICAL COMPANY 2004-11-23 US disclosed
US-20040029720-A1 Supported group 8-10 transition metal olefin polymerization catalysts EASTMAN CHEMICAL COMPANY 2004-02-12 US disclosed
US-6660677-B1 Supported group 8-10 transition metal olefin polymerization catalysts EASTMAN CHEMICAL COMPANY 2003-12-09 US disclosed
US-20020058768-A1 Supported group 8-10 transition metal Olefin polymerization catalysts E. I. DU PONT DE NEMOURS AND COMPANY 2002-05-16 US disclosed
US-6303720-B1 E.G., NICKEL COMPLEX OF 2,3-BIS(2,6-DIMETHYLPHENYLIMINO)-(1,4)-DITHIANE EASTMAN CHEMICAL COMPANY 2001-10-16 US disclosed
US-6103658-A Olefin polymerization catalysts containing group 8-10 transition metals, processes employing such catalysts and polymers obtained therefrom EASTMAN CHEMICAL COMPANY (US) 2000-08-15 US disclosed