Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.50 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520212 | 0.89 | MAPK1 (0.58) | KMT2ALMNASMN1; SMN2MEN1NLRP3 | |
| SCHEMBL29383617 | 0.89 | MAPK1 (0.58) | KMT2ALMNASMN1; SMN2MEN1NLRP3 | |
| SCHEMBL5533057 | 0.86 | SMN1; SMN2 (0.51) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL462304 | 0.83 | LPAR1 (0.66) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL6429941 | 0.83 | KMT2A (0.65) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL8845511 | 0.82 | KMT2A (0.68) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL1726368 | 0.82 | KMT2A (0.62) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL9678852 | 0.81 | KMT2A (0.57) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL9678861 | 0.81 | KMT2A (0.57) | KMT2ALMNASMN1; SMN2MEN1TDP1 | |
| SCHEMBL9723542 | 0.80 | NLRP3 (0.55) | KMT2ALMNASMN1; SMN2MEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046549-A1 | ANTI-NEURODEGENERATIVELY EFFECTIVE XANTHENE DERIVATIVES | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | claimed |
| CN-104530702-B | Stabilizer composition, preparation method of stabilizer composition and molded composition formed by stabilizer composition | 金发科技股份有限公司 | 2017-01-18 | — | — | CN | disclosed |
| CN-104530702-A | Stabilizer composition, preparation method of stabilizer composition and molded composition formed by stabilizer composition | KINGFA SCIENCE & TECHNOLOGY CO | 2015-04-22 | — | — | CN | disclosed |
| CN-1127479-C | Sulfonylurea derivatives and their use in the control of interleukin-1 activity | PFIZER (US) | 2003-11-12 | — | — | CN | disclosed |
| EP-0556322-A1 | AMINOSULFONYL UREA ACAT INHIBITORS. | WARNER LAMBERT CO (US) | 1993-08-25 | — | — | EP | disclosed |