SCHEMBL2947587

SCHEMBL2947587

C=C(C)C(=O)Nc1c(C(C)C)cccc1C(C)C

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
LMNA P02545 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
RXFP1 Q9HBX9 1/20 0.49
TDP1 Q9NUW8 2/20 0.48
MEN1 O00255 1/20 0.48
NLRP3 Q96P20 2/20 0.47
LPAR1 Q92633 1/20 0.47
SOAT2 O75908 1/20 0.46
SOAT1 P35610 1/20 0.46
MAPK1 P28482 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6429941 0.87 KMT2A (0.65) KMT2ALMNASMN1; SMN2TDP1MEN1
SCHEMBL30977624 0.81 KMT2A (0.64) KMT2ALMNASMN1; SMN2TDP1MEN1
SCHEMBL30977623 0.81 KMT2A (0.64) KMT2ALMNASMN1; SMN2TDP1MEN1
SCHEMBL1726368 0.81 KMT2A (0.62) KMT2ALMNASMN1; SMN2TDP1MEN1
SCHEMBL9850986 0.79 KMT2A (0.61) KMT2ALMNASMN1; SMN2TDP1MEN1
SCHEMBL462304 0.79 LPAR1 (0.66) KMT2ALMNASMN1; SMN2TDP1MEN1
SCHEMBL14943787 0.79 LMNA (0.55) KMT2ALMNASMN1; SMN2TDP1MEN1
SCHEMBL18415612 0.79 KMT2A (0.56) KMT2ALMNASMN1; SMN2TDP1MEN1
SCHEMBL11170777 0.77 ALDH1A1 (0.61) KMT2ALMNARXFP1TDP1MEN1
SCHEMBL8845511 0.77 KMT2A (0.68) KMT2ALMNASMN1; SMN2TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2029668-B1 METHOD FOR FORMING EXFOLIATED CLAY-POLYOLEFIN NANOCOMPOSITES UNIV CALIFORNIA (US) 2016-09-21 EP disclosed
EP-2038343-B1 METHOD FOR FORMING FLAME-RETARDANT CLAY-POLYOLEFIN COMPOSITES UNIV CALIFORNIA (US) 2015-08-12 EP disclosed
US-7776943-B2 Method for forming exfoliated clay-polyolefin nanocomposites THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-17 US disclosed
US-7772299-B2 combining a layered mineral such as montmorillonite and chlorite with a transition metal catalyst that becomes activated upon contact; using the activated catalyst-filler to polymerize an olefin; the silicate layered structure is disrupted THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-08-10 US disclosed
US-7754789-B1 Method for forming flame-retardant clay-polyolefin composites THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-13 US disclosed
US-20100168310-A1 METHOD FOR FORMING FLAME-RETARDANT CLAY-POLYOLEFIN COMPOSITES REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2010-07-01 US disclosed
US-20090318587-A1 METHOD FOR FORMING FLAME-RETARDANT CLAY-POLYOLEFIN COMPOSITES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2009-12-24 US disclosed
EP-2038343-A2 METHOD FOR FORMING FLAME-RETARDANT CLAY-POLYOLEFIN COMPOSITES The Regents of the University of California (US) 2009-03-25 EP disclosed
EP-2029668-A2 METHOD FOR FORMING EXFOLIATED CLAY-POLYOLEFIN NANOCOMPOSITES The Regents of the University of California (US) 2009-03-04 EP disclosed
US-20080275164-A1 Method for forming exfoliated clay-polyolefin nanocomposites REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2008-11-06 US disclosed
WO-2008108790-A2 METHOD FOR FORMING FLAME-RETARDANT CLAY-POLYOLEFIN COMPOSITES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-09-12 WO disclosed
WO-2007146263-A2 METHOD FOR FORMING EXFOLIATED CLAY-POLYOLEFIN NANOCOMPOSITES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-12-21 WO disclosed