SCHEMBL6429964

SCHEMBL6429964

S/C(=C(\S)c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.58
CA4 P22748 2/20 0.58
CA12 O43570 2/20 0.58
CA1 P00915 2/20 0.58
CA9 Q16790 2/20 0.58
CA3 P07451 1/20 0.58
CA6 P23280 1/20 0.58
CA5A P35218 1/20 0.58
CA7 P43166 1/20 0.58
CA13 Q8N1Q1 1/20 0.58
CA14 Q9ULX7 1/20 0.58
CA5B Q9Y2D0 1/20 0.58
CES1 P23141 5/20 0.47
CES2 O00748 4/20 0.47
TSHR P16473 2/20 0.47
ALDH1A1 P00352 2/20 0.47
DAO P14920 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
TDP1 Q9NUW8 4/20 0.43
F2 P00734 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2883723 1.00 CA2 (0.58) CA2CA4CA12CA1CA9
SCHEMBL2883726 1.00 CA2 (0.58) CA2CA4CA12CA1CA9
SCHEMBL29291444 0.87 CA2 (0.52) CA2CA4CA12CA1CA9
SCHEMBL28921747 0.84 CA2 (0.50) CA2CA4CA12CA1CA9
SCHEMBL12262995 0.82 CA12 (0.48) CA2CA4CA12CA1CA9
SCHEMBL2387567 0.80 ESR1 (0.46) CA2CA4CA12CA1CA9
SCHEMBL2387569 0.80 ESR1 (0.46) CA2CA4CA12CA1CA9
SCHEMBL3805878 0.79
SCHEMBL17504065 0.79 CA2 (0.58) CA2CA4CA12CA1CA9
SCHEMBL19662378 0.78 SMN1; SMN2 (0.53) TSHRTDP1MAPTPOLBPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020056044-A1 MODIFIED ARCHAEAL FAMILY B POLYMERASES Singular Genomics Systems, Inc. (US) 2020-03-19 WO disclosed
WO-2019164977-A1 FLUORINATED NUCLEOTIDES AND USES THEREOF Singular Genomics Systems, Inc. (US) 2019-08-29 WO disclosed
WO-2017205336-A1 NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2017-11-30 WO disclosed
CN-106349816-A AQUEOUS INK, INK CARTRIDGE, INK DRYING SYSTEM, INK DRYING METHOD, RECORDING APPARATUS, AND RECORDING METHOD 富士施乐株式会社 2017-01-25 CN disclosed
US-20110144366-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2011-06-16 US disclosed
EP-1385024-B1 NEAR INFRARED ABSORBTION FILM BRIDGESTONE CORP (JP) 2010-05-19 EP disclosed
US-20050062402-A1 Flat display panel with a front protection plate ASAHI GLASS COMPANY, LIMITED (JP) 2005-03-24 US disclosed
US-6833665-B2 Flat display panel with a front protection plate ASAHI GLASS COMPANY, LIMITED (JP) 2004-12-21 US disclosed
US-20030085649-A1 Flat display panel ASAHI GLASS COMPANY, LIMITED (JP) 2003-05-08 US disclosed
EP-1280179-A2 Flat display panel ASAHI GLASS COMPANY LTD. (JP) 2003-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144366-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AP1M1, L1CAM, SOD1 CA2 1955/4885CA4 2758/4885CA12 1542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.