Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298247 | 0.87 | ALDH1A1 (0.55) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL9016040 | 0.77 | HPRT1 (0.64) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL9576782 | 0.76 | ALDH1A1 (0.42) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL4612665 | 0.68 | ALDH1A1 (0.46) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL18600603 | 0.67 | HSD17B10 (0.50) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| Chrysene SCHEMBL28354167 | 0.66 | HPRT1 (0.78) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL5858906 | 0.66 | CYP2A6 (0.60) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL4959304 | 0.66 | PTPN22 (0.60) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL18242724 | 0.66 | HSD17B10 (0.50) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL2098692 | 0.66 | ALDH1A1 (0.50) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050210535-A1 | Parasite integral membrane protein for use as tool in identifying modulators and devlopment of vaccines for prevention and treatment of toxoplasmosis | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2005-09-22 | — | — | US | disclosed |
| US-6902926-B1 | Toxoplasma gondii apical membrane antigen-1 | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2005-06-07 | — | — | US | disclosed |