SCHEMBL4612665

SCHEMBL4612665

Ic1ccc2cc3ccccc3cc2c1I

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.46
HSD17B10 Q99714 6/20 0.46
HIF1A Q16665 2/20 0.46
CYP1B1 Q16678 1/20 0.46
KDM4E B2RXH2 3/20 0.38
GAA P10253 2/20 0.38
TDP1 Q9NUW8 3/20 0.38
CYP3A4 P08684 3/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HBB P68871 1/20 0.38
CYP1A2 P05177 5/20 0.38
ERBB2 P04626 1/20 0.38
FYN P06241 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
AHR P35869 1/20 0.38
CYP2A6 P11509 5/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25221463 0.78 ALOX5 (0.48) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL17710478 0.78 CYP1A2 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL24787457 0.78 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL1298247 0.78 ALDH1A1 (0.55) ALDH1A1HSD17B10HIF1ACYP1B1TDP1
SCHEMBL15511865 0.78 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL6694549 0.77 PLAU (0.38) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL4848746 0.77 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL29532882 0.77 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL4853659 0.77 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E
SCHEMBL23664 0.77 ALDH1A1 (0.72) ALDH1A1HSD17B10HIF1ACYP1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5576417-A Method for synthesizing aromatic polymers DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-11-19 US claimed
CN-113166043-A Electrolyte for sulfur-based magnesium battery 富士胶片和光纯药株式会社 2021-07-23 CN disclosed
EP-1520846-B1 Method for producing polymerized hydrocarbon JFE CHEMICAL CORP (JP) 2008-03-05 EP disclosed
US-7138484-B2 Method for producing polymerized hydrocarbon JFE CHEMICAL CORPORATION (JP) 2006-11-21 US disclosed
CN-1234709-C Biporphin metal coordination compound with bridge linking face-face structure and its use SHANDONG SCIENCE & ENGINEERING (CN) 2006-01-04 CN disclosed
US-20050075478-A1 Method for producing polymerized hydrocarbon JFE CHEMICAL CORPORATION (JP) 2005-04-07 US disclosed
EP-1520846-A1 Method for producing polymerized hydrocarbon JFE Chemical Corporation (JP) 2005-04-06 EP disclosed
US-20040197484-A1 Coating liquid for forming insulating film and method for producing insulating film SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-07 US disclosed
CN-1472211-A Biporphin metal coordination compound with bridge linking face-face structure and its use 山东理工大学 2004-02-04 CN disclosed
US-5576417-A Method for synthesizing aromatic polymers DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1996-11-19 US disclosed