Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.43 |
| ▸ | RARG | P13631 | 16/20 | 0.43 |
| ▸ | RARB | P10826 | 15/20 | 0.43 |
| ▸ | RARA | P10276 | 10/20 | 0.43 |
| ▸ | RXRG | P48443 | 8/20 | 0.43 |
| ▸ | RXRB | P28702 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436608 | 0.82 | RXRA (0.66) | RXRARARGRARBRARARXRG | |
| SCHEMBL7943902 | 0.81 | RARB (0.67) | RXRARARGRARBRARARXRG | |
| SCHEMBL7943899 | 0.81 | RARB (0.67) | RXRARARGRARBRARARXRG | |
| SCHEMBL7943904 | 0.81 | RARB (0.67) | RXRARARGRARBRARARXRG | |
| SCHEMBL8198622 | 0.80 | RARG (0.65) | RXRARARGRARBRARARXRG | |
| SCHEMBL6257667 | 0.80 | RARG (0.65) | RXRARARGRARBRARARXRG | |
| SCHEMBL32671443 | 0.80 | RARG (0.65) | RXRARARGRARBRARARXRG | |
| SCHEMBL8919744 | 0.79 | RXRA (0.44) | RXRARARGRARBRARARXRG | |
| SCHEMBL10775733 | 0.74 | RARB (0.46) | RXRARARGRARBRARARXRG | |
| SCHEMBL10773071 | 0.73 | RARB (0.49) | RXRARARGRARBRARARXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567172-A2 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | GPC Biotech AG (DE) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050101-A3 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004050101-A2 | FORMULATIONS USEFUL AGAINST HEPATITIS C VIRUS INFECTIONS | GPC BIOTECH AG (DE) | 2004-06-17 | — | — | WO | disclosed |