Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.44 |
| ▸ | RARG | P13631 | 13/20 | 0.44 |
| ▸ | RARB | P10826 | 13/20 | 0.44 |
| ▸ | RXRB | P28702 | 12/20 | 0.44 |
| ▸ | RXRG | P48443 | 12/20 | 0.44 |
| ▸ | RARA | P10276 | 8/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430449 | 0.79 | RXRA (0.43) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7879971 | 0.79 | TP53 (0.42) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7943904 | 0.78 | RARB (0.67) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7943899 | 0.78 | RARB (0.67) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7943902 | 0.78 | RARB (0.67) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL8919757 | 0.77 | RXRA (0.38) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7778758 | 0.74 | TP53 (0.43) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL10775733 | 0.74 | RARB (0.46) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL10773071 | 0.73 | RARB (0.49) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL7876468 | 0.71 | RXRA (0.66) | RXRARARGRARBRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802897-A1 | NOVEL COMPOUNDS | Smithkline Beecham S.p.A. (IT) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021638-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM S.P.A. (IT) | 1996-07-18 | — | — | WO | disclosed |