Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.39 |
| ▸ | HTR3B | O95264 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2473095 | 0.87 | MAOA (0.59) | AKT2PNMTMAOAMAOBTAAR1 | |
| Hydrochloric Acid SCHEMBL21879608 | 0.85 | MAOB (0.57) | AKT2PNMTMAOAMAOBTAAR1 | |
| SCHEMBL9667972 | 0.83 | SLC6A4 (0.50) | AKT2PNMTMAOAMAOBTAAR1 | |
| SCHEMBL5218251 | 0.83 | PNMT (0.50) | AKT2PNMTMAOAMAOBTAAR1 | |
| SCHEMBL208131 | 0.82 | AOC3 (0.43) | AKT2PNMTMAOAMAOBTAAR1 | |
| SCHEMBL28219677 | 0.81 | MAOA (0.44) | MAOAMAOBTAAR1IDO1KDM1A | |
| SCHEMBL208130 | 0.81 | AOC3 (0.44) | PNMTTAAR1CYP3A4IDO1AGXT | |
| SCHEMBL12585406 | 0.79 | AKT2 (0.49) | AKT2PNMTMAOAMAOBTAAR1 | |
| Formic Acid SCHEMBL6207884 | 0.78 | MAOA (0.49) | AKT2PNMTMAOAMAOBTAAR1 | |
| SCHEMBL23827531 | 0.72 | MAOA (0.44) | MAOAMAOBKDM1ASLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558254-A2 | A PROCESS FOR PREPARING PHARMACEUTICAL COMPOSITIONS CONTAINING 4-AMINOQUINOLINES COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS OF THE EYE, COMPOSITIONS RESULTING THEREFROM | Raut, Rajeev (IN) | 2005-08-03 | — | — | EP | claimed |
| WO-2003097025-A2 | A PROCESS FOR PREPARING PHARMACEUTICAL COMPOSITIONS CONTAINING 4-AMINOQUINOLINES COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS OF THE EYE AND COMPOSITIONS RESULTING THEREFROM | RAUT RAJEEV (IN) | 2003-11-27 | — | — | WO | claimed |