Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.54 |
| ▸ | TUBB | P07437 | 4/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.54 |
| ▸ | NQO1 | P15559 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6430874 | 1.00 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9097880 | 0.86 | NQO1 (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9097877 | 0.86 | NQO1 (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9097327 | 0.84 | POLB (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9097324 | 0.84 | POLB (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4990078 | 0.84 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4990091 | 0.84 | TUBB4A (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9096892 | 0.83 | NQO1 (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9096889 | 0.83 | NQO1 (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18889671 | 0.82 | TUBB4A (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9708310-B2 | Phenanthroindolizidine and phenanthroquinolizidine alkaloid having a hydroxyl group on the phenanthrene ring thereof, preparation method and use thereof | CHINA MEDICAL UNIVERSITY (TW) | 2017-07-18 | — | — | US | disclosed |
| EP-1066227-B1 | PROCESS OF PREPARING DISCOTIC LIQUID CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2005-12-28 | — | — | EP | disclosed |
| US-6534135-B1 | Process of preparing discotic liquid crystalline compounds | MERCK PATENT GESELLSCHAFT (DE) | 2003-03-18 | — | — | US | disclosed |
| EP-1066227-A1 | PROCESS OF PREPARING DISCOTIC LIQUID CRYSTALLINE COMPOUNDS | MERCK PATENT GmbH (DE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048844-A1 | PROCESS OF PREPARING DISCOTIC LIQUID CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 1999-09-30 | — | — | WO | disclosed |