Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30966536 | 0.84 | PSEN1 (0.42) | GAATDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL12627563 | 0.80 | ALDH1A1 (0.43) | GAATDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL6431991 | 0.75 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL2201723 | 0.74 | TLR8 (0.43) | GAALMNAALDH1A1MAPTNPSR1 | |
| SCHEMBL28421317 | 0.73 | LMNA (0.46) | GAATDP1L3MBTL1LMNAALDH1A1 | |
| SCHEMBL8974064 | 0.73 | NR5A1 (0.45) | LMNAALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL8975367 | 0.73 | NR5A1 (0.45) | LMNAALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL202536 | 0.73 | NR5A1 (0.45) | LMNAALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL20678395 | 0.73 | NR5A1 (0.45) | LMNAALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL12918761 | 0.73 | NR5A1 (0.45) | LMNAALDH1A1MAPTPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066227-B1 | PROCESS OF PREPARING DISCOTIC LIQUID CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2005-12-28 | — | — | EP | disclosed |
| US-6534135-B1 | Process of preparing discotic liquid crystalline compounds | MERCK PATENT GESELLSCHAFT (DE) | 2003-03-18 | — | — | US | disclosed |
| EP-1066227-A1 | PROCESS OF PREPARING DISCOTIC LIQUID CRYSTALLINE COMPOUNDS | MERCK PATENT GmbH (DE) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999048844-A1 | PROCESS OF PREPARING DISCOTIC LIQUID CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 1999-09-30 | — | — | WO | disclosed |