SCHEMBL6430893

SCHEMBL6430893

Nc1ccccc1OC(=O)c1ccccc1N

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.60
HSD17B10 Q99714 11/20 0.60
CFTR P13569 1/20 0.60
TSHR P16473 4/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
KDM4E B2RXH2 7/20 0.51
HPGD P15428 5/20 0.51
GLA P06280 2/20 0.51
RAB9A P51151 3/20 0.49
POLB P06746 3/20 0.49
NPC1 O15118 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
MAPK1 P28482 1/20 0.49
HIF1A Q16665 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
NFKB1 P19838 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2579668 0.89 HSD17B10 (0.56) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2
SCHEMBL17744800 0.84 HSD17B10 (0.47) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2
SCHEMBL8632649 0.84 MAPT (0.50) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2
SCHEMBL30277562 0.83 KMT2A (0.60) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2
SCHEMBL28260593 0.83 HSD17B10 (0.51) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2
SCHEMBL11794621 0.83 KMT2A (0.60) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2
SCHEMBL17744884 0.83 ALDH1A1 (0.50) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2
SCHEMBL27906638 0.83 ALDH1A1 (0.58) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2
SCHEMBL9861291 0.82 HSD17B10 (0.71) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2
SCHEMBL13292717 0.82 SMN1; SMN2 (0.63) ALDH1A1HSD17B10CFTRTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240206059-A1 LOW-DIELECTRIC BOARD MATERIAL NITTO DENKO CORPORATION (JP) 2024-06-20 US disclosed
US-10400076-B2 Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES, INC. (JP) 2019-09-03 US disclosed
CN-105392838-B Composition epoxy resin, prepreg and carbon fibre reinforced composite 东丽株式会社 2018-12-14 CN disclosed
EP-3020763-B1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES (JP) 2018-08-29 EP disclosed
US-20160152785-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL TORAY INDUSTRIES, INC. (JP) 2016-06-02 US disclosed
EP-3020763-A1 EPOXY RESIN COMPOSITION, PREPREG, AND CARBON FIBER-REINFORCED COMPOSITE MATERIAL Toray Industries, Inc. (JP) 2016-05-18 EP disclosed
CN-105392838-A Epoxy resin composition, prepreg, and carbon fiber-reinforced composite material TORAY INDUSTRIES 2016-03-09 CN disclosed
US-20050114882-A1 Information providing system and paper-shaped display medium DAI NIPPON PRINTING CO., LTD. (JP) 2005-05-26 US disclosed
EP-1489540-A1 INFORMATION PROVIDING SYSTEM AND PAPER-SHAPED DISPLAY MEDIUM DAI NIPPON PRINTING CO., LTD. (JP) 2004-12-22 EP disclosed
US-6576747-B1 Reacting alkylenediol and isatoic anhydride in presence of 1,4-diazabicyclo(2.2.2)octane and/or N,N,N*,N*-tetramethylenediamine; heating, decyclization, salt formation XEROX CORPORATION 2003-06-10 US disclosed
US-5220057-A Fiber-reactive dyes susitable for dyeing and printing hydroxyl- and amido-containing materials BAYER AKTIENGESELLSCHAFT (DE) 1993-06-15 US disclosed
US-5187187-A Compounds, e.g. 1-(4-bromoacetamidobenzyl)-5-methoxy-2-methylindole or a similar anthranilic acid derivative, as antiinflammatory agents, affinity labelling agents and ligands in chromatography TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1993-02-16 US disclosed
US-5068250-A 1-(4-bromoacetamidobenzyl)-5-methoxy-2-methylindole-3-acetic acid or anthranilic acid derivatives TRUSTEES OF UNIVERSITY OF PENNSYLVANIA (US) 1991-11-26 US disclosed