Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705548 | 0.88 | OPRM1 (0.34) | MAPTKIF11 | |
| SCHEMBL5705361 | 0.88 | OPRM1 (0.34) | MAPTKIF11 | |
| SCHEMBL6430921 | 0.74 | CNR2 (0.39) | NPC1MAPTRAB9AKIF11CNR2 | |
| SCHEMBL6180988 | 0.72 | ACACB (0.46) | KIF11CNR2CNR1 | |
| SCHEMBL6797392 | 0.68 | TSHR (0.46) | NPC1MAPTRAB9ATSHRKIF11 | |
| SCHEMBL19678203 | 0.68 | FFAR4 (0.42) | CNR2CNR1 | |
| SCHEMBL19678206 | 0.68 | ACACB (0.42) | KIF11 | |
| SCHEMBL10264393 | 0.68 | ACACB (0.42) | KIF11CNR2CNR1 | |
| SCHEMBL19678200 | 0.68 | FFAR4 (0.42) | CNR2CNR1 | |
| SCHEMBL3286655 | 0.67 | HDAC6 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539127-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017952-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |