Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431085 | 0.90 | TACR1 (0.55) | TACR1 | |
| SCHEMBL6431261 | 0.87 | TACR1 (0.67) | TACR1 | |
| SCHEMBL6367959 | 0.86 | CTRB1 (0.62) | TACR1 | |
| SCHEMBL6431079 | 0.85 | TACR1 (0.69) | TACR1 | |
| SCHEMBL30866227 | 0.83 | TACR1 (0.53) | TACR1 | |
| SCHEMBL9140655 | 0.81 | ACE (0.50) | TACR1 | |
| SCHEMBL6428866 | 0.80 | ITGB1 (0.68) | — | |
| SCHEMBL30050973 | 0.80 | ITGB1 (0.57) | TACR1 | |
| SCHEMBL31599475 | 0.80 | SLC6A2 (0.54) | TACR1 | |
| SCHEMBL29697171 | 0.80 | SLC6A2 (0.54) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001764-A4 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2005-08-24 | — | — | EP | claimed |
| JP-2002512625-A | — | — | 2002-04-23 | — | — | JP | claimed |
| EP-1001764-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999064395-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-12-16 | — | — | WO | claimed |
| WO-1998053814-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1998-12-03 | — | — | WO | claimed |