SCHEMBL29697171

SCHEMBL29697171

C[C@H](O)[C@@H](N)C(=O)N1CCCC[C@H]1C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.54
TACR1 P25103 19/20 0.52
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31599475 1.00 SLC6A2 (0.54) SLC6A2TACR1MAPT
SCHEMBL29696994 0.88 TACR1 (0.48) SLC6A2TACR1MAPT
SCHEMBL29696977 0.86 NMUR2 (0.56) SLC6A2
SCHEMBL31599477 0.86 OPRM1 (0.49) SLC6A2
SCHEMBL30866227 0.84 TACR1 (0.53) SLC6A2TACR1
SCHEMBL29697005 0.84 NMUR2 (0.57) SLC6A2
SCHEMBL29453074 0.83 SLC6A2 (0.65) SLC6A2
SCHEMBL29697064 0.83 NMUR2 (0.55)
SCHEMBL30424040 0.81 SLC6A2 (0.62) SLC6A2
SCHEMBL30051364 0.80 DPP3 (0.60) SLC6A2TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861268-B Cell penetrating peptides and methods of making and using the same 恩特拉达治疗学股份有限公司 2025-04-01 CN disclosed
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2025-01-09 US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 SLC6A2 2612/4885TACR1 770/4885MAPT 3736/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 SLC6A2 2612/4885TACR1 770/4885MAPT 3736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.