Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 17/20 | 0.67 |
| ▸ | CCKAR | P32238 | 13/20 | 0.67 |
| ▸ | CBLB | Q13191 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643231 | 0.88 | CCKBR (0.71) | CCKBRCCKAR | |
| SCHEMBL20867001 | 0.84 | CCKBR (0.52) | CCKBRCCKARCBLB | |
| SCHEMBL643031 | 0.84 | CCKBR (0.74) | CCKBRCCKAR | |
| SCHEMBL3969962 | 0.83 | CCKBR (0.58) | CCKBRCCKAR | |
| SCHEMBL641924 | 0.83 | CCKBR (0.83) | CCKBRCCKAR | |
| SCHEMBL642047 | 0.82 | CCKBR (0.91) | CCKBRCCKAR | |
| SCHEMBL2180869 | 0.81 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL18394473 | 0.81 | CCKBR (0.76) | CCKBRCCKAR | |
| SCHEMBL2930364 | 0.81 | CCKBR (0.76) | CCKBRCCKAR | |
| SCHEMBL18394863 | 0.81 | CCKBR (0.76) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119630-B2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | ARROW THERAPEUTICS LIMITED (GB) | 2012-02-21 | — | — | US | disclosed |