Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.91 |
| ▸ | CCKAR | P32238 | 11/20 | 0.91 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526707 | 0.95 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9526696 | 0.95 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9526843 | 0.93 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL641924 | 0.93 | CCKBR (0.83) | CCKBRCCKAR | |
| SCHEMBL9526638 | 0.93 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9526387 | 0.92 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL9526895 | 0.92 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL643278 | 0.92 | CCKBR (0.85) | CCKBRCCKARBDKRB1 | |
| SCHEMBL9526394 | 0.92 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL643031 | 0.90 | CCKBR (0.74) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853204-B2 | Pharmaceutical composition comprising a benzodiazepine derivative and an inhibitor of the RSV fusion protein | ARROW THERAPEUTICS LIMITED (GB) | 2014-10-07 | — | — | US | claimed |
| EP-1727550-B1 | PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBITOR OF THE RSV FUSION PROTEIN | ARROW THERAPEUTICS LTD (GB) | 2009-07-29 | — | — | EP | claimed |
| US-20070293482-A1 | Process for Preparing Benzodiazepines | NOVARTIS PHARMACEUTICALS CORPORATION (US) | 2007-12-20 | — | — | US | claimed |
| US-20070142403-A1 | Pharmaceutical composition comprising a benzodiazepine derivative and an inhibitor of the rsv fusion protein | NOVARTIS PHARMACEUTICALA CORPORATION (US) | 2007-06-21 | — | — | US | claimed |
| EP-1727550-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBITOR OF THE RSV FUSION PROTEIN | Arrow Therapeutics Limited (GB) | 2006-12-06 | — | — | EP | claimed |
| WO-2005090319-A1 | PROCESS FOR PREPARING BENZODIAZEPINES | ARROW THERAPEUTICS LIMITED (GB) | 2005-09-29 | — | — | WO | claimed |
| WO-2005089769-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBIT OR OF THE RSV FUSION PROTEIN | ARROW THERAPEUTICS LIMITED (GB) | 2005-09-29 | — | — | WO | claimed |
| US-8853204-B2 | Pharmaceutical composition comprising a benzodiazepine derivative and an inhibitor of the RSV fusion protein | ARROW THERAPEUTICS LIMITED (GB) | 2014-10-07 | — | — | US | disclosed |
| EP-1441715-B1 | LIPOXINS AND ASPIRIN-TRIGGERED LIPOXINS AND THEIR STABLE ANALOGS IN THE TREATMENT OF ASTHMA AND INFLAMMATORY AIRWAY DISEASES | BRIGHAM & WOMENS HOSPITAL (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-1911448-B1 | Lipoxins and Aspirin-triggered lipoxins and their stable analogs in the treatment of asthma and inflammatory airway diseases | BRIGHAM & WOMENS HOSPITAL (US) | 2013-01-02 | — | — | EP | disclosed |
| US-20120149771-A1 | METHOD FOR TREATING AIRWAY HYPER-RESPONSIVENESS WITH LIPOXIN ANALOGS | THE BRIGHAM AND WOMEN'S HOSPITAL (US) | 2012-06-14 | — | — | US | disclosed |
| US-8119630-B2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | ARROW THERAPEUTICS LIMITED (GB) | 2012-02-21 | — | — | US | disclosed |
| US-8119691-B2 | Method for treating airway hyper-responsiveness with lipoxin analogs | NATIONAL INSTITUTES OF HEALTH (NIH) (US) | 2012-02-21 | — | — | US | disclosed |
| WO-2005090319-A1 | PROCESS FOR PREPARING BENZODIAZEPINES | ARROW THERAPEUTICS LIMITED (GB) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005089769-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A BENZODIAZEPINE DERIVATIVE AND AN INHIBIT OR OF THE RSV FUSION PROTEIN | ARROW THERAPEUTICS LIMITED (GB) | 2005-09-29 | — | — | WO | disclosed |
| EP-1539716-A1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Arrow Therapeutics Limited (GB) | 2005-06-15 | — | — | EP | disclosed |
| EP-1441715-A1 | LIPOXINS AND ASPIRIN-TRIGGERED LIPOXINS AND THEIR STABLE ANALOGS IN THE TREATMENT OF ASTHMA AND INFLAMMATORY AIRWAY DISEASES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2004026843-A1 | BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ARROW THERAPEUTICS LIMITED (GB) | 2004-04-01 | — | — | WO | disclosed |
| US-20030166716-A1 | Lipoxins and aspirin-triggered lipoxins and their stable analogs in the treatment of asthma and inflammatory airway diseases | BRIGHAM AND WOMEN'S HOSPITAL, THE | 2003-09-04 | — | — | US | disclosed |
| WO-2003039533-A1 | LIPOXINS AND ASPIRIN-TRIGGERED LIPOXINS AND THEIR STABLE ANALOGS IN THE TREATMENT OF ASTHMA AND INFLAMMATORY AIRWAY DISEASES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149771-A1 | METHOD FOR TREATING AIRWAY HYPER-RESPONSIVENESS WITH LIPOXIN ANALOGS | LTB4R, LTB4R2, ALOX15B | CCKBR 2983/4885CCKAR 3213/4885BDKRB1 235/4885 |
| US-20070293482-A1 | Process for Preparing Benzodiazepines | CNR1, SIGMAR1, GABRA3 | CCKBR 246/4885CCKAR 114/4885BDKRB1 217/4885 |
| US-20030166716-A1 | Lipoxins and aspirin-triggered lipoxins and their stable analogs in the treatment of asthma and inflammatory airway diseases | ALOX15B, LTA4H, ALOX15 | CCKBR 4261/4885CCKAR 3572/4885BDKRB1 672/4885 |
| US-20070142403-A1 | Pharmaceutical composition comprising a benzodiazepine derivative and an inhibitor of the rsv fusion protein | GABRP, TSPO, GABRA1 | CCKBR 2243/4885CCKAR 2354/4885BDKRB1 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.