Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431361 | 0.81 | HDAC3 (0.59) | ALDH1A1MEN1KMT2AHTTALOX12 | |
| SCHEMBL6858498 | 0.78 | HDAC3 (0.65) | ALDH1A1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL1701693 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL3062971 | 0.75 | POLB (0.54) | ALDH1A1MEN1KMT2AHTTALOX12 | |
| SCHEMBL27761963 | 0.75 | CTSD (0.64) | ALDH1A1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL11470090 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHDAC3HDAC1 | |
| SCHEMBL3077377 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MEN1KMT2AALOX12HDAC3 | |
| SCHEMBL3077991 | 0.72 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2AHTTL3MBTL1 | |
| SCHEMBL5365743 | 0.72 | EPHX1 (0.55) | ALDH1A1MEN1KMT2AL3MBTL1ALPL | |
| SCHEMBL25682729 | 0.72 | HDAC3 (0.57) | ALDH1A1MEN1KMT2AHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171423-B1 | CARBAMIC ACID DERIVATIVES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2005-01-12 | — | — | EP | disclosed |