Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 8/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27454399 | 0.81 | PGR (0.40) | HTR2CPGRBACE1KCNH2 | |
| SCHEMBL27453578 | 0.78 | PGR (0.40) | PGRKCNH2 | |
| SCHEMBL7037061 | 0.78 | HTR2C (0.35) | HTR2CPGRESR2ALOX5TAAR1 | |
| SCHEMBL7559730 | 0.78 | PGR (0.44) | PGRCXCR3TAAR1 | |
| SCHEMBL27469701 | 0.77 | CA12 (0.31) | — | |
| SCHEMBL27455026 | 0.76 | PGR (0.36) | PGRBACE1 | |
| SCHEMBL7543641 | 0.76 | PGR (0.42) | PGRCXCR3 | |
| SCHEMBL27455027 | 0.76 | TSHR (0.44) | PGR | |
| SCHEMBL27472102 | 0.73 | GABRA1 (0.32) | — | |
| SCHEMBL27545377 | 0.72 | PDPK1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515725-A4 | USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS | WYETH CORP (US) | 2005-09-21 | — | — | EP | claimed |
| CN-1665510-A | Derivatives of cyclic thiocarbamate derivatives as PR modulators and their use for treating skin disorders | WYETH CORP (US) | 2005-09-07 | — | — | CN | claimed |
| CN-1662241-A | Use of cyclic thiocarbamate derivatives in the treatment of hormone-related disorders | WYETH CORP (US) | 2005-08-31 | — | — | CN | claimed |
| EP-1515725-A2 | USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS | Wyeth (US) | 2005-03-23 | — | — | EP | claimed |
| CN-1179753-C | Contraceptive compositions contaiing antiprogesting and progestinic | — | 2004-12-15 | — | — | CN | claimed |
| CN-1145618-C | Cyclocarbamate derivatives as progesterone receptor modulators | �Ʒ� | 2004-04-14 | — | — | CN | claimed |
| WO-2004000801-A2 | USE OF CYCLOTHIOCARBAMATE DERIVATIVES IN TREATMENT OF HORMONE-RELATED CONDITIONS | WYETH (US) | 2003-12-31 | — | — | WO | claimed |
| CN-1131856-C | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PRODUCTS CORP. (US) | 2003-12-24 | — | — | CN | claimed |
| CN-1349517-A | Cyclocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | claimed |
| CN-1349516-A | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | claimed |
| CN-1349415-A | Contraceptive compositions contaiing antiprogesting and progestinic | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | claimed |
| CN-1665510-A | Derivatives of cyclic thiocarbamate derivatives as PR modulators and their use for treating skin disorders | WYETH CORP (US) | 2005-09-07 | — | — | CN | disclosed |
| CN-1662241-A | Use of cyclic thiocarbamate derivatives in the treatment of hormone-related disorders | WYETH CORP (US) | 2005-08-31 | — | — | CN | disclosed |
| CN-1179753-C | Contraceptive compositions contaiing antiprogesting and progestinic | — | 2004-12-15 | — | — | CN | disclosed |
| CN-1145618-C | Cyclocarbamate derivatives as progesterone receptor modulators | �Ʒ� | 2004-04-14 | — | — | CN | disclosed |
| CN-1349517-A | Cyclocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1349516-A | Cyclothiocarbamate derivatives as progesterone receptor modulators | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| CN-1349415-A | Contraceptive compositions contaiing antiprogesting and progestinic | AMERICAN HOME PROD (US) | 2002-05-15 | — | — | CN | disclosed |
| EP-1175411-A1 | CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | American Home Products Corporation (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066570-A1 | CYCLOTHIOCARBAMATE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |