Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.60 |
| ▸ | ITGAV | P06756 | 20/20 | 0.60 |
| ▸ | ITGB6 | P18564 | 9/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.49 |
| ▸ | ITGB8 | P26012 | 8/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432161 | 1.00 | ITGB3 (0.60) | ITGB3ITGAVITGB6ITGB1ITGA2B | |
| SCHEMBL6435940 | 0.85 | ITGAV (0.53) | ITGB3ITGAVITGB6ITGB1ITGA2B | |
| SCHEMBL6435942 | 0.85 | ITGAV (0.53) | ITGB3ITGAVITGB6ITGB1ITGA2B | |
| SCHEMBL6303762 | 0.83 | ITGAV (0.60) | ITGB3ITGAVITGB6ITGB1ITGA2B | |
| SCHEMBL6303755 | 0.83 | ITGAV (0.60) | ITGB3ITGAVITGB6ITGB1ITGA2B | |
| SCHEMBL7443091 | 0.82 | ITGB3 (0.66) | ITGB3ITGAVITGB6ITGB1ITGA2B | |
| SCHEMBL7443095 | 0.82 | ITGB3 (0.66) | ITGB3ITGAVITGB6ITGB1ITGA2B | |
| SCHEMBL6220968 | 0.82 | ITGAV (0.52) | ITGB3ITGAVITGB6ITGB1ITGA2B | |
| SCHEMBL6220962 | 0.82 | ITGAV (0.52) | ITGB3ITGAVITGB6ITGB1ITGA2B | |
| SCHEMBL6431924 | 0.78 | ITGAV (0.82) | ITGB3ITGAVITGB6ITGB1ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040111-B1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2005-06-22 | — | — | EP | disclosed |