Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.66 |
| ▸ | ITGAV | P06756 | 20/20 | 0.66 |
| ▸ | ITGB6 | P18564 | 10/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.58 |
| ▸ | ITGB5 | P18084 | 8/20 | 0.51 |
| ▸ | ITGB8 | P26012 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443091 | 1.00 | ITGB3 (0.66) | ITGB3ITGAVITGB6ITGA2BITGB1 | |
| SCHEMBL7434333 | 0.90 | ITGAV (0.81) | ITGB3ITGAVITGB6ITGA2BITGB1 | |
| SCHEMBL7440561 | 0.90 | ITGAV (0.81) | ITGB3ITGAVITGB6ITGA2BITGB1 | |
| SCHEMBL7434321 | 0.90 | ITGAV (0.81) | ITGB3ITGAVITGB6ITGA2BITGB1 | |
| SCHEMBL7434705 | 0.85 | ITGAV (0.49) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL7434712 | 0.85 | ITGAV (0.49) | ITGB3ITGAVITGB6ITGB5ITGB8 | |
| SCHEMBL14608716 | 0.84 | ITGAV (0.66) | ITGB3ITGAVITGB6ITGA2BITGB5 | |
| SCHEMBL6432161 | 0.82 | ITGB3 (0.60) | ITGB3ITGAVITGB6ITGA2BITGB1 | |
| SCHEMBL6432159 | 0.82 | ITGB3 (0.60) | ITGB3ITGAVITGB6ITGA2BITGB1 | |
| SCHEMBL14608717 | 0.82 | ITGAV (0.68) | ITGB3ITGAVITGB6ITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410526-B1 | BONE DISORDERS; RESTENOSIS; VISION DISORDERS; ANTICHOLESTEROL AGENTS; ANTICANCER, ANTITUMOR AGENTS | MERCK & CO., INC. | 2002-06-25 | — | — | US | disclosed |