Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 5/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745039 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL6747067 | 0.83 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8018667 | 0.81 | SLC2A1 (0.39) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL6744267 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL8018671 | 0.79 | MMP9 (0.39) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL27886667 | 0.79 | MEN1 (0.42) | MMP9MMP1MEN1KMT2AMMP2 | |
| SCHEMBL14768367 | 0.79 | MEN1 (0.42) | MMP9MMP1MEN1KMT2AMMP2 | |
| SCHEMBL3217271 | 0.78 | SLC2A1 (0.49) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL25620259 | 0.78 | SLC2A1 (0.49) | SLC2A1MMP13MMP9ADAM17MMP1 | |
| SCHEMBL25620258 | 0.78 | SLC2A1 (0.49) | SLC2A1MMP13MMP9ADAM17MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539127-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017952-A1 | METHOD OF TREATING OSTEOARTHRITIS | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |