Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCKBR | P32239 | 12/20 | 0.46 |
| ▸ | CCKAR | P32238 | 9/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3177281 | 0.88 | MEN1 (0.60) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL3965441 | 0.85 | MEN1 (0.49) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL4416283 | 0.78 | CCKBR (0.57) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL11831521 | 0.78 | MEN1 (0.62) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL644146 | 0.77 | CCKBR (0.62) | CCKBRCCKAR | |
| SCHEMBL641925 | 0.74 | LMNA (0.70) | MEN1KMT2ACCKBROPRK1 | |
| SCHEMBL3183396 | 0.74 | CCKBR (0.48) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL3186746 | 0.74 | MEN1 (0.57) | MEN1KMT2ACCKBRCCKAR | |
| SCHEMBL11822036 | 0.73 | MEN1 (0.60) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL20867074 | 0.70 | CCKBR (0.72) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119630-B2 | Benzodiazepine derivatives and pharmaceutical compositions containing them | ARROW THERAPEUTICS LIMITED (GB) | 2012-02-21 | — | — | US | disclosed |