SCHEMBL6433036

SCHEMBL6433036

CCCCNC(C)C[Si](OC)(OC)OC

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11741311 0.82 CASP2 (0.30)
SCHEMBL5011389 0.79 PAOX (0.32) LMNATSHR
SCHEMBL753884 0.78
SCHEMBL28985263 0.77 LMNA (0.34) LMNA
SCHEMBL21239939 0.77
SCHEMBL28981783 0.76 LMNA (0.33) LMNAALDH1A1TSHR
SCHEMBL2523181 0.76 CA12 (0.39) LMNAALDH1A1
SCHEMBL28985262 0.75 LMNA (0.37) LMNATSHR
SCHEMBL114225 0.73 TSHR (0.37) LMNAALDH1A1TSHR
Hydrochloric Acid SCHEMBL6130780 0.73 LMNA (0.41) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150299540-A1 SPECIFIC AMINOALKYL-FUNCTIONAL ALKOXYSILOXANE OLIGOMER MIXTURES, PROCESS FOR PRODUCTION THEREOF AND USE THEREOF EVONIK INDUSTRIES AG (DE) 2015-10-22 US disclosed
EP-2922894-A1 SPECIFIC AMINOALKYL-FUNCTIONAL ALKOXYSILOXANE-OLIGOMER MIXTURES, PROCESSES FOR PRODUCING SAME AND USE OF SAME Evonik Degussa GmbH (DE) 2015-09-30 EP disclosed
WO-2014079614-A1 SPECIFIC AMINOALKYL-FUNCTIONAL ALKOXYSILOXANE-OLIGOMER MIXTURES, PROCESSES FOR PRODUCING SAME AND USE OF SAME EVONIK INDUSTRIES AG (DE) 2014-05-30 WO disclosed
EP-1304345-B1 Aminoalkylalkoxysiloxan containing mixtures , their preparation process and their use DEGUSSA (DE) 2005-12-14 EP disclosed
US-6770327-B2 Aminoalkylalkoxysiloxane mixtures DEGUSSA AG (DE) 2004-08-03 US disclosed
EP-1304345-A2 Aminoalkylalkoxysiloxan containing mixtures , their preparation process and their use Degussa AG (DE) 2003-04-23 EP disclosed
US-20030072873-A1 Aminoalkylalkoxysiloxane mixtures DEGUSSA AG (DE) 2003-04-17 US disclosed