Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | CDC25A | P30304 | 1/20 | 0.69 |
| ▸ | CDC25B | P30305 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22047108 | 0.92 | ALDH1A1 (0.86) | ALDH1A1LMNAKDM4ECDC25ACDC25B | |
| SCHEMBL4212548 | 0.91 | ALDH1A1 (0.84) | ALDH1A1LMNAKDM4ECDC25ACDC25B | |
| SCHEMBL22046629 | 0.90 | ALDH1A1 (0.79) | ALDH1A1LMNAKDM4ECDC25ACDC25B | |
| SCHEMBL4211826 | 0.89 | ALDH1A1 (1.00) | ALDH1A1LMNAKDM4ECDC25ACDC25B | |
| SCHEMBL4204209 | 0.88 | LMNA (0.80) | ALDH1A1LMNAKDM4ECDC25ACDC25B | |
| SCHEMBL4203424 | 0.88 | ALDH1A1 (0.72) | ALDH1A1LMNAKDM4ECDC25ACDC25B | |
| SCHEMBL18183449 | 0.87 | CYP3A4 (0.67) | ALDH1A1LMNAKDM4EGAATSHR | |
| SCHEMBL4203793 | 0.86 | LMNA (0.77) | ALDH1A1LMNAKDM4EGAATSHR | |
| SCHEMBL6404590 | 0.86 | ALDH1A1 (0.77) | ALDH1A1LMNAKDM4ECDC25ACDC25B | |
| SCHEMBL4214464 | 0.86 | LMNA (0.77) | ALDH1A1LMNAKDM4ECDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885LMNA 4116/4885KDM4E 3676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.