Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 15/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.37 |
| ▸ | PLA2G2E | Q9NZK7 | 2/20 | 0.37 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.37 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433278 | 0.87 | PLA2G2A (0.45) | F10PLA2G2APLA2G1BPLA2G10PLA2G5 | |
| SCHEMBL6433340 | 0.73 | F10 (0.85) | F10 | |
| SCHEMBL6436680 | 0.72 | PLA2G2A (0.41) | F10PLA2G2A | |
| Hydrochloric Acid SCHEMBL6434386 | 0.70 | F10 (0.55) | F10PLA2G2A | |
| SCHEMBL6435208 | 0.69 | F10 (0.71) | F10PLA2G10 | |
| SCHEMBL28742466 | 0.69 | F10 (0.47) | F10 | |
| SCHEMBL6435201 | 0.69 | F10 (0.81) | F10 | |
| SCHEMBL6433741 | 0.68 | F10 (0.61) | F10 | |
| SCHEMBL6435752 | 0.68 | F10 (0.53) | F10 | |
| SCHEMBL6433028 | 0.67 | PLA2G2A (0.44) | F10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042287-B1 | INDOLE DERIVATIVES AS INHIBITORS OF FACTOR XA | AVENTIS PHARMA GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6337344-B1 | ANTICOAGULANTS AND ENZYME INHIBITORS FOR CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-08 | — | — | US | disclosed |