Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433409 | 0.78 | HTT (0.44) | HRH3HTR1AHTR7HTR6SLC6A2 | |
| SCHEMBL6327555 | 0.73 | CYP3A4 (0.47) | HRH3HTR1ASLC6A2SLC6A3HTT | |
| SCHEMBL3540053 | 0.66 | GBA1 (0.38) | — | |
| SCHEMBL5668812 | 0.63 | — | — | |
| SCHEMBL10041855 | 0.63 | MAOB (0.50) | HRH3SLC6A2SLC6A3MAOBMAOA | |
| SCHEMBL3278335 | 0.62 | TSHR (0.48) | HRH3HTR1ASLC6A2SLC6A3MAOB | |
| SCHEMBL11437031 | 0.62 | CTSL (0.44) | HRH3SLC6A2SLC6A3HTTMAOB | |
| SCHEMBL17072360 | 0.62 | GSTP1 (0.49) | HRH3SLC6A2SLC6A3MAOBMAOA | |
| SCHEMBL3864944 | 0.62 | HRH3 (0.41) | HRH3SLC6A4HTTFOXM1CYP2D6 | |
| SCHEMBL3864942 | 0.62 | HRH3 (0.41) | HRH3SLC6A4HTTFOXM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | claimed |