Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | DRD3 | P35462 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435288 | 1.00 | MTNR1A (0.37) | MTNR1ADRD2HTR2ADRD3CA12 | |
| SCHEMBL7063724 | 0.86 | NPC1 (0.47) | MTNR1ADRD2HTR2ADRD3MTNR1B | |
| SCHEMBL7063726 | 0.86 | NPC1 (0.47) | MTNR1ADRD2HTR2ADRD3MTNR1B | |
| SCHEMBL7213965 | 0.85 | CA12 (0.36) | DRD3CA12CA1CA9PREP | |
| SCHEMBL6434340 | 0.82 | CA12 (0.39) | CA12CA1CA9PREPCYP4F2 | |
| SCHEMBL6433353 | 0.82 | EPHX1 (0.43) | — | |
| SCHEMBL6433347 | 0.82 | EPHX1 (0.43) | — | |
| SCHEMBL6486732 | 0.81 | PGR (0.37) | DRD2HTR2ADRD3CA12CA1 | |
| SCHEMBL6433894 | 0.81 | PGR (0.37) | DRD2HTR2ADRD3CA12CA1 | |
| SCHEMBL6485691 | 0.81 | PGR (0.37) | DRD2HTR2ADRD3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165495-B1 | RESORCINOL DERIVATIVES | PFIZER (US) | 2005-04-20 | — | — | EP | disclosed |