SCHEMBL6433771

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6434323	0.86	PLAU (0.51)	PLAUPLATDGAT2PLGLATS1
	SCHEMBL6432989	0.86	PLAU (0.46)	PLAUPLATDGAT2PLGLPAR1
	SCHEMBL6433828	0.82	PLAU (0.74)	PLAUPLATPLGSMN1; SMN2
	SCHEMBL6436521	0.81	PLAU (0.72)	PLAUPLATPLG
	SCHEMBL6435537	0.76	PLAU (0.56)	PLAUPLATPLG
	SCHEMBL6436084	0.75	PLAU (0.41)	PLAUPLATDGAT2PLG
	SCHEMBL7367423	0.73	POLB (0.46)	F2NPC1MAPT
	SCHEMBL7367854	0.73	PPARG (0.42)	PLAUDGAT2PLGNPC1MAPT
	Hydrochloric Acid SCHEMBL6436188	0.72	PLAU (0.59)	PLAUPLATPLG
	SCHEMBL6433790	0.72	PLAU (0.60)	PLAUPLATPLGSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.