SCHEMBL6434238

SCHEMBL6434238

CCOc1cccc(-c2ccc(C3CCN(S(=O)(=O)[C@]4(C(=O)OC)C[C@@H]5OC(C)(C)O[C@@H]5C4)CC3)cc2C)n1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 7/20 0.52
MMP3 P08254 7/20 0.52
MMP1 P03956 2/20 0.52
MMP9 P14780 2/20 0.52
MMP14 P50281 2/20 0.52
FFAR4 Q5NUL3 2/20 0.33
GUCY1A1 Q02108 9/20 0.32
GUCY1B1 Q02153 9/20 0.32
TLR9 Q9NR96 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6438551 1.00 MMP2 (0.52) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6439739 0.93 MMP2 (0.51) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6969017 0.93 MMP2 (0.51) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6439735 0.93 MMP2 (0.51) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6438940 0.92 MMP2 (0.55) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6435055 0.92 MMP2 (0.55) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6435058 0.92 MMP2 (0.55) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6433456 0.90 MMP2 (0.55) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6433500 0.85 MMP2 (0.49) MMP2MMP3MMP1MMP9MMP14
SCHEMBL6436938 0.83 MMP2 (0.55) MMP2MMP3MMP1MMP9MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050026836-A1 Composition for the treatment of damaged tissue DACK KEVIN NEIL (GB) 2005-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026836-A1 Composition for the treatment of damaged tissue MMP1, SERPINE1, COL14A1 MMP2 19/4885MMP3 28/4885MMP1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.